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Nonlinear optical imaging with a scanning fiber-optic endomicroscope

By: Bhujwalla, Z.; Kakkad, S.; Yongping Chen; Jiefeng Xi; Glunde, K.; Murari, K.; Xingde Li; Yuying Zhang; Ming-Jun Li;

2011 / IEEE / 978-986-02-8974-9

Description

This item was taken from the IEEE Conference ' Nonlinear optical imaging with a scanning fiber-optic endomicroscope ' We present recent updates on our work on developing a fully integrated, miniaturized fiber-optic scanning endomicroscope for performing nonlinear optical imaging including two-photon fluorescence and second harmonic generation. We describe our design approaches for significantly improving signal collection efficiency and resolution. Preliminary tissue imaging results will be presented to demonstrate the potential of the nonlinear endomicroscopy technology for diagnostics and image-based guidance.