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Transcutaneous measurement of bio-substances by suction effusion fluid from skin

By: Ito, N.; Shinohara, S.; Miyamoto, S.; Nagata, N.; Takatani, O.; Kimura, J.; Kikuchi, M.; Arai, T.; Kayashima, S.; Kuriyama, T.;

1989 / IEEE

Description

This item was taken from the IEEE Periodical ' Transcutaneous measurement of bio-substances by suction effusion fluid from skin ' Successful transcutaneous blood glucose monitoring on human subjects has been achieved. Effusion fluid is collected from the skin using a recently developed suction apparatus, and glucose concentration in the fluid is measured. During a 75-g oral glucose tolerance test on normal subjects, frequent transcutaneous monitoring of blood glucose change was achieved with an improved ion-sensitive field effect transistor glucose sensor which can measure glucose concentration in only 5- mu l samples.<>